The United States has already administered 1,200 monkeypox vaccines

Other cases are occurring around the world. Countries are moving forward with studies and actions. In the United States, vaccines have already begun to be administered.

As the number of monkeypox cases [ou “varíola dos macacos”] rising, in an ongoing global outbreak, U.S. health workers said Friday they were stepping up testing and contact tracing and expanding access to vaccines and treatments.

As part of those efforts, about 1,200 doses of vaccines against the disease have been administered in the United States, he said. Raj Panjabi, White House senior director for global health security and biodefense.

“We want to ensure that those exposed to high risk have rapid access to vaccines and, if they become ill, can receive appropriate treatment. To date, we have delivered around 1,200 vaccines,” Panjabi said. “And 100 treatment courses for eight jurisdictions, and we have more to offer the states.”

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Massachusetts healthcare workers treating patients with monkeypox were among the first to receive vaccines, to be protected against the virus.

In the United States, the two-dose Jynneos vaccine is licensed to prevent smallpox, specifically monkeypox. Another smallpox vaccine licensed in the United States, ACAM2000, can also be used for monkeypox.

To date, more than 120 PCR tests have been performed in the United States as part of outbreak monitoring. “That’s only a fraction of what’s available,” Panjabi said, adding that 67 labs in 46 states — part of a network known as the Laboratory Response Network — have the “collective capability” to perform more than 1,000 tests per day.

“So what we’re working on now is making sure the testing capacity is being utilized,” he said. People with symptoms of monkeypox are encouraged to see a medical professional, and professionals are urged to test if they suspect someone may have monkeypox.

There could be ‘community-level’ spread, CDC officially warns

On Friday, officials from the US Centers for Disease Control and Prevention urged clinicians to be on the lookout for possible cases of monkeypox, as the virus could spread at the community level.

Twenty cases of monkeypox have been identified in 11 states, along with an additional case in the United States who was infected and tested elsewhere, said Jennifer McQuiston, deputy director of the CDC’s Division of Pathogens and High-Consequence Pathologies. .

All patients are recovering or have already recovered, and those who still have a rash are advised to stay home and isolate themselves from others until fully recovered.

“I want to emphasize that this could happen in other parts of the United States. There could be community-wide transmission, which is why we really want to increase our surveillance efforts,” said McQuiston. “We really want to encourage doctors that if they see a rash and they’re worried it’s monkeypox, they go ahead and get tested.”

McQuiston added that the rashes that appear as a result of monkeypox infections in this outbreak can be subtle and easily confused with other types of infections, especially sexually transmitted ones – and there may be co-infections. of monkeypox with sexually transmitted diseases (STDs).

McQuiston said the rash from a monkeypox infection usually appears as “deep” and “well-rounded” lesions that progress to raised or fluid-filled pustules. It can be confused with other infectious diseases such as herpes or syphilis, he added.

“Having said that, we don’t want to downplay this condition. The rash caused by monkeypox virus can spread widely throughout the body or be present in sensitive areas like the genitals,” McQuiston said. “It can be very painful, and some patients have reported needing prescription medication to deal with the pain. The wounds can also cause long-term scarring of the skin.”

An analysis of genetic sequence data from cases in the United States indicates that two genetically distinct variants of monkeypox may be circulating, McQuiston said.

Genetic sequence data is “certainly interesting from a scientific perspective”, but “to determine how long the monkeypox virus has been circulating for, it will take analyzing a lot more sequences from a lot more patients to start putting this puzzle together more clearly.” she said. “It’s certainly possible that there were cases of monkeypox in the United States that went unnoticed earlier, but not on a large scale.”

McQuiston added that the risk to the public is still low and finding cases with distinct lineages is a “positive sign” that the country’s surveillance network is working.

CDC investigators and healthcare professionals released a report on Friday describing numerous cases of monkeypox in the United States, noting that “ongoing research suggests person-to-person community transmission, and the CDC urges health departments , clinicians, and the public to remain vigilant, institute adequate infection prevention and control measures, and notify public health authorities of suspected cases in order to reduce the spread of disease.

Of the 17 cases described in the report in nine states, all patients had a rash, 14 of them said they had traveled abroad in the 21 days before their symptoms, and all but one were identified as being a man who has had sex with men. (MSM). Three of them were immunocompromised. All patients were adults.

“The high proportion of first cases diagnosed in this epidemic among people who identify as gay, bisexual or other MSM may simply reflect an early introduction of monkeypox into interconnected social networks; this finding may also reflect an ascertainment bias due to strong relationships and established among select MSM and clinical professionals with robust STD services and broad knowledge of infectious diseases, including rare conditions,” the CDC investigators wrote in the report.

“However, infections are often not limited to certain geographic areas or population groups, as close physical contact with infected people can spread McQuiston: anyone, regardless of gender or sexual orientation, can contracting and spreading monkeypox.”

Globally, according to World Health Organization officials, more and more countries are reporting cases of monkeypox that have never seen the virus before.

“Cases have been reported in 26 countries” where the virus is not endemic, Maria Van Kerkhove, WHO technical officer and covid-19 technical lead, said Thursday at a press conference. She added that more than 600 cases have been identified in these countries.

“As surveillance increases, as attention increases, we expect more cases to be identified,” she said. “Many public health outbreak investigations are ongoing.”

Rosamund Lewis, WHO’s technical lead for monkeyopx, said on Tuesday that this outbreak is different from previous ones because “we are seeing all the cases appear in a relatively short period of time.”

“What we’re seeing now started as a small cluster of cases, then investigation quickly led to the discovery of infections in a cluster of men who have sex with men, and that led to other investigations, so we still don’t know what the real source of the outbreak is,” Lewis said. “What’s more important now is not to stigmatize.”

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